Registered Clinical Investigations
MMSx Authority conducts registered clinical investigations aligned with international ethical and research standards. All interventional studies are pre-registered on ClinicalTrials.gov prior to data collection, and conducted under GCP ICH E6(R3) and the Declaration of Helsinki (2013).
Study Registry — ClinicalTrials.gov
| Study | NCT Registration | Design | n | Sites | Status |
|---|---|---|---|---|---|
| MOVE Protocol Movement-Oriented Velocity of Engagement |
NCT07220200 | Multi-site interventional case-series · 8-week · 4-phase | 40 | GFFI New Delhi · BodyGNTX USA · IIKBS | Completed · Published |
| BPIT Pilot Study 5-Line Principle — Strength, HRV & Injury Risk |
NCT07296640 | Prospective single-site · Paired t-tests α=0.05 · Cohen's d | 23 | BodyGNTX USA | Completed · Published |
| BPIT Multi-Cohort Validation International Cross-Site Reproducibility |
NCT07256717 | Multi-cohort observational · 5 sites · Mixed-effects ANOVA | 369 agg. 392 |
BodyGNTX · GFFI · IIKBS · AIHFT · BFS | Preprint · Under Review |
Key Outcomes by Study
Significant improvements in pain indices, functional capacity, balance performance, and sit-to-stand metrics across geographically diverse sites (India & USA). Published in JMMBS.
15–25% strength gains, clinically significant HRV improvement, and measurable reduction in knee valgus angle. Pre-registered SAP. DOI: 10.5281/zenodo.17594977.
Reproducible strength, HRV, and injury-mitigation outcomes across 5 international sites — establishing cross-site reproducibility of BPIT. n=369 (agg. 392). DOI: 10.5281/zenodo.17551763.
Ethics & Compliance
- GCP ICH E6(R3) — Good Clinical Practice guidelines for all registered investigations
- Declaration of Helsinki (2013 revision) — ethical principles for human subjects research
- Pre-registered Statistical Analysis Plans (SAPs) locked before data collection begins
- Independent statistician verification of all primary analyses
- Open datasets archived on OSF and Zenodo (CC BY 4.0) for independent verification
- Conflict of interest disclosure on all publications